hepatocarcinoma metástasis

Introduction. HES1 promotes invasiveness and metastasis in vivo; therefore, an over-expression of HES1 and under-expression of Deltex1 are seen in osteosarcoma conditions. Angiotensinogen, a member of the serpin family, is involved in the suppression of tumor growth and metastasis. [7] A study in autopsy files showed that unusual extrahepatic metastatic sites include diaphragm, pancreas, gall bladder, stomach, colon, adrenal gland, pleura, peritoneum, cervical lymph nodes, brain, skin, and oral cavity.[8]. J Hepatol 2012;56:908-43. In conclusion, our study reveals that QHF can inhibit the proliferation, migration and invasion of HCCLM3, and this effect may be related to inhibiting HGF/c-Met signaling pathway. Katyal S, Oliver JH 3rd, Peterson MS, Ferris JV, Carr BS, Baron RL. 13. Routine greyscale ultrasound, contrast-enhanced ultrasound, and intra-operative ultrasound all have roles to play. The patient also exhibited tumor metastases to the lungs, left knee, little finger of the left hand, scalp, and the skin of the neck. 16. 19. Hepatocyte growth factor/c-mesenchymal-epithelial transition factor (HGF/c-Met) signaling has attracted much attention, which is mediated by tyrosine kinases and expressed in a wide variety of . To study metastasis, we have in vivo established mammalian tumor cell lines, among them the hepatocarcinoma (He/De), the nephroblastoma (Ne/De), the melanoma (Me/De), the myeloblastic nephroma (My1/De and My2/De) cell lines. Se encontró adentro – Página 271from hepatocellular carcinoma receiving externalbeam radiotherapy. Cancer. 2009;115:2710–20. 70. Cho HS, Oh JH, Han I, Kim HS. Survival of patients with skeletal metastases from hepatocellular carcinoma after surgical management. The find-ings in this study suggest a great potential of CH50 in gene ther-apy of hepatocarcinoma. Se encontró adentro – Página 46hepatocarcinoma cell lines have high and no metastatic potential in lymph nodes respectively. ... “To investigate the effects of GnT-IVa on the metastasis of hepatocarcinoma, exogenous GnT-IVa was introduced into Hepa1-6 cells, ... with wash-out); helpful feature in distinguishing a metastasis from a, perilesional enhancement is most commonly seen in, Eovist is often useful for detection and confirmation of metastatic disease, on the delayed phase, metastatic lesion do not retain any Eovist and essentially appear as "holes" in the liver, central scar, with persistent delayed enhancement, 1. The tendency of hepatocarcinoma to metastasize results in a high rate of mortality, making it a hot research topic in cancer studies. The demographics are strongly influenced by the regions in which chronic hepatitis B infection . 2014;:175-82. Surg 1991;20:371-4. Department of Pathology, the Second Xiangya Hospital. HCC is the third leading cause of cancer-related death worldwide. Multiple staging systems for disease-free survival after metastasectomy have been proposed and are being refined. 6. Western blotting, quantitative real-time PCR and immunohistochemistry were used to . Tumor metastasis is one of the main causes of the high mortality of hepatocellular carcinoma (HCC). Int J Clin Exp Pathol 2013;6:816-20. The appearance of liver metastases on MRI is also variable, but MRI is more sensitive than CT for the detection of liver metastases 5. World J Gastroenterol 2013;19:3512-6. Drug therapy was maintained for 3 months, when the patient was readmitted due to clinical worsening, with the development of jaundice and severe ascites. http://dx.doi.org/10.20517/2394-5079.2016.01, Download PDF Arrelaro RC, Ji Shi Department of Biochemistry, Dalian Medical University, Dalian 116044, China; Department of Pathology, The First Affiliated Hospital of China Medical University, Anshan Hospital . Se encontró adentro – Página 147... hepatic metastasis of colon carcinoma 133 hepatitis B virus 1 hepatitis C virus 1, 53 hepatocellular carcinoma (HCC) 1, 47, 53, 59, 69, 91, 117 hepatoma 37 immunomodulation 133 interferon 53 interleukin-2 133 intrahepatic metastasis ... The following articles are especially welcome: pathogenesis, clinical examination and early diagnosis of hepatoma, complications of hepatoma, and their preventions and treatments, etc. Tumour cell metastasis is characteristic of tumour progression involving complex processes including the ability to dissolve the basement membrane and the extracellular matrix (ECM) and to migrate through the ECM. 14. . Experimental Metastasis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Experimental Metastasis in a compact format. See also: ultrasound appearance of hepatic metastases. 9. 15. Poletti PB. These authors contributed equally to this work. https://doi.org/10.1016/j.biopha.2020.110867. What Defines ‘cure’ After Liver Resection for Colorectal Metastases? 13. Metástasis en clivus de hepatocarcinoma asociado a quimiembolización transarterial hepática. Editorial Policies transient hepatic attenuation differences (THADs), focal fatty sparing / focal fatty change) may further muddy the waters. 1992;159(5):1005-9. Tumor metastasis is the major cause of tumor related death, Hca-F is a hepatocarcinoma cell line presenting highly lymph node metastasis, we study from analysis of genome to the analysis of proteome, and got Ech1 gene candidates concordantly expressed increase both at mRNA and protein level in the Hca-F cell highly lymph node metastasis. Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. However, the exact role and underlying mechanism of ETV6 in HCC remain unclear. Reference article, Radiopaedia.org. Lin, Eugene.. If you have any queries or need any help, please contact us at support@oaepublish.com. Hellenic J Surg. 2011;83(2):98-101. Tumor metastasis is the major cause of tumor related death, Hca-F is a hepatocarcinoma cell line presenting highly lymph node metastasis, we study from analysis of genome to the analysis of proteome, and got Ech1 gene candidates concordantly expressed increase both at mRNA and protein level in the Hca-F cell highly lymph node metastasis. A tomographic study revealed a contrast-enhanced expansive heterogeneous mass measuring 9.7 cm × 5.1 cm × 5.6 cm at this largest diameter and located on the left midline of the anterior mediastinum, with no clear interface between mediastinum and pericardium. © 2016-2021 OAE Publishing Inc., except certain content provided by third parties, Extracellular Vesicles and Circulating Nucleic Acids, Journal of Cancer Metastasis and Treatment, Journal of Translational Genetics and Genomics, Journal of Smart Environments and Green Computing, Journal of Surveillance, Security and Safety, Journal of Environmental Exposure Assessment, http://creativecommons.org/licenses/by-nc-sa/3.0/, Patient with HCC of 8.6 cm in segment 4 liver, underwent transcatheter arterial embolization and following the appearance of mediastinal injury of 4 cm in the right paratracheal region, 3 lesions of HCC, 2 years after liver transplant tumor recurrence in the upper mediastinum, 2 patients with hepatitis-C related HCC, after several courses of TACE developed mediastinal and pericardial neoplastic growth, HCC 3 cm treated with TACE; 2 years after presents hoarseness, a chest CT scan revealed a 5-cm tumor over the aortopulmonary window of the mediastinum, HCC with liver mass 11 cm ×13 cm with vena cava invasion and extension to the right atrium (4 cm × 4 cm ), HCC with associated thrombus was found to extend from the liver through the inferior vena cava into the right atrium, Right intraventricular metastasis from HCC in a patient who had undergone a partial hepatectomy for HCC more than two years earlier, Systemic chemotherapy with cisplatin and doxorubicin, HCC who was incidentally found to have an intracavitary mass completely occupying the right atrium, HCC with hepatectomy; 1 year after patient started to present dyspnea, hoarseness, palpitation, chest CT scan showed a mass of 4 cm in the left heart ventricle and myocardial invasion, The first patient was noted to have a large RV tumor mass with intracavitary growth and myocardial invasion; the second had massive pulmonary and LA metastasis; and the third patient had a right atrial tumor mass with concomitant RV and LA involvement, Patient with pulmonary metastases from HCC, who presented with a tumor in the left lung, extending to the left atrium through the left pulmonary vein. Hepatocarcinoma is a common and aggressive cancer that is strongly associated with chronic infection by the hepatitis B virus (HBV) [].Poor prognosis and patient survival with hepatocarcinoma are largely due to invasion/metastasis and postsurgical recurrence [].Invasion and metastasis are fundamental properties of hepatocellular carcinoma (HCC), which has a very high mortality rate. Aunque suele presentarse en hígados cirróticos, excepcionalmente se desarrolla sobre un hígado no cirrótico. Spam, offensive content, impersonation, and private information will not be permitted. Liver metastases are typically hypoattenuating on unenhanced CT, enhancing less than surrounding liver following contrast 1. *P < 0.05, **P < 0.01. Cases of mediastinal metastases reported in the literature, HCC: hepatocellular carcinoma; TACE: transcatheter arterial chemoembolization; RV: right ventricular; LA: left atrial. Radiologia 2010;52:385-98. Generalmente se diagnostica a personas de 50 años de edad o más. We describe a case of hepatocellular carcinoma metastatic to the anterior mandibular gingivae of a 60-year-old man. 29, No. Mice with pulmonary metastasis were marked "1", and mice without pulmonary metastasis were marked "0". Cardiac metastasis of hepatocellular carcinoma in a young non-cirrhotic patient, to the left ventricle. [2] HCC is usually associated with liver cirrhosis, which may impair treatment tolerability and thus increase the risk of complications in cases of advanced cirrhosis. Noncolorectal, Nonneuroendocrine Liver Metastases. Histopathologic study confirmed the diagnosis of moderately differentiated trabecular hepatocarcinoma with lymph node and left renal metastasis. Transarterial chemotherapy and radioembolization are other options for treatment for hepatic metastases. An adaptor protein CRKL plays a pivotal role in HCC growth, whereas miR-124-3p downregulation is associated with clinical stage and the poor survival of patients. Achkar JP, Araya V, Baron RL, Marsh JW, Dvorchik I, Rakela J. Undetected hepatocellular carcinoma: clinical features and outcome after liver transplantation. Paschalidis N, Kalaitzis J, Voultsos M, Marinis A, Rizos S. Primary Non-Hodgkin Lymphoma of the Liver Mimicking Metastases. 18. 38. This dissertation, "Roles of Hypoxia-inducible MicroRNA-210 in Hepatocellular Carcinoma" by Ka-lun, Alan, Kai, 奚家麟, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: ... Fukuoka K, Masachika E, Honda M, Tsukamoto Y, Nakano T. Isolated metastases of hepatocellular carcinoma in the left atrium, unresponsive to treatment with sorafenib. Because most liver cancers are observed in association with cirrhosis, it is important to consider the severity of liver disease before a treatment strategy is planned. All values are presented as the mean ± SEM. Tatokoro M & Kihara K. Liver Metastases from Ureteral and Bladder Cancer. Hepatocarcinoma with metastasis to the anterior mediastinum. Axial contrast-enhanced computed tomography slices at arterial (A) and portal (B) phases. No mediastinal lymphadenomegaly was detected. Subclinical metastasis is the major cause of tumor recurrence and . Fluid-fluid levels are considered a specific finding for neuroendocrine tumor metastases 9. The Student t test was used to analyze the differences. Gastroenterología y Hepatología, Vol. Additionally, pseudolesions (e.g. The mechanism and pathogenesis of the high frequency of intrahepatic metastasis in hepatocellular carcinoma (HCC) has not yet been elucidated. 2020;21(2):e74-82. 16. Immunotherapy for hepatocellular carcinoma: the force awakens in HCC? Zhang X, Liu S, Hu T, He Y, Sun S. Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression. Hepatology (Baltimore, Md). Consent form was obtained from the patient family. 2. AFP levels reached 45,000 ng/mL. Several studies identified the presence of ANGPTL4 in various solid tumors, such as breast cancer, colorectal cancer, prostate cancer, hepatocarcinoma, and renal cell carcinoma [103-107], suggesting its important role in cancer growth and progression, anoikis resistance, altered redox regulation, angiogenesis, and metastasis [80, 104, 108 . Surg 1991;20:371-4. Auer LS, Laboratory findings were as follows: hemoglobin = 10.5 g/dL; hematocrit = 34%; leukocytes = 7,500.000/mm3 (segmented: 64%, band cells: 0%, lymphocytes: 28%, eosinophils: 5%, monocytes: 3%, basophils: 1%); total bilirubin = 0.7 mg/dL; alanine aminotransferase = 48 U/L; aspartate aminotransferase = 40 U/L; AFP = 14,000 ng/mL; gamma-glutamyl transferase = 350 U/L; alkaline phosphatase = 148 U/L; international normalized ratio = 1.75; creatinine = 0.77 mg/dL. Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviors. News Although an acidic tumor microenvironment has been proven to promote cancer metastasis, the underlying regulatory mechanisms remain poorly defined. Szjenfeld D, Hepatocellular carcinoma with mediastinal and pericardial invasion: report of two cases. Kimakura M, Abe T, Nagahara A et al. This dissertation, "Dual-tracer Positron Emission Tomography in the Evaluation of Primary & Metastatic Hepatocellular Carcinoma" by Chi-lai, Ho, 何志禮, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being ... In these cases, biopsy and tissue biomarkers, such as AFP, are used to confirm the diagnosis. Innate Immune Cell-Derived Microparticles Facilitate Hepatocarcinoma Metastasis by Transferring Integrin M 2 to Tumor Cells August 2013 The Journal of Immunology 191(6) Casado AC, 7. Up to 20% of patients undergoing metastasectomy for this indication remain disease-free 10. A case of hepatocellular J Laryng Otol 1974;88:981-2. carcinoma diagnosed by mandibular metastasis. Sung AD, Cheng S, Moslehi J, Scully EP, Prior JM, Loscalzo J. Hepatocellular carcinoma with intracavitary cardiac involvement: a case report and review of the literature. Hepatocellular carcinoma is one of the most common fatal malignan cies of mankind. The metastasized lymph nodes included the popliteal, inguinal, and iliac artery lymph nodes. Published by Elsevier Masson SAS. Sakai T, Oka Y, Kurokawa S, et al. The scent fingerprint of hepatocarcinoma: in-vitro metastasis prediction with volatile organic compounds (VOCs) Background: Hepatocellular carcinoma (HCC) is a common and aggressive form of cancer. 15. He was a former smoker of 90 packs a year and denied alcohol abuse. 10. Yang Y, Ye YC. Yan Li 1, Zhenhua Zhai 2, Dan Liu 1, Xinping Zhong 3, Xin Meng 4, Qingquan Yang 5, Jingang Liu 1 & Hangyu Li 1,6 Tumor Biology volume 36, pages 737-745 (2015)Cite this article Fluid–fluid Level in Hepatic Metastases: A Characteristic Sign of Metastases of Neuroendocrine Origin. Figure 1. with no distant metastases, may undergo partial liver resection, which is potentially curative, as well as liver transplantation or percutaneous ablation. . Therefore, an understanding of the various appearances of metastatic disease is crucial. Hepatocellular carcinoma is the fifth most common cancer in the world and is the third most common cause of cancer-related death (after lung and stomach cancer). Kanda M, Tateishi R, Yoshida H, Sato T, Masuzaki R, Ohki T, Imamura J, Goto T, Yoshida H, Hamamura K, Obi S, Kanai F, Shiina S, Omata M. Extrahepatic metastasis of hepatocellular carcinoma: incidence and risk factors. Murine ascites hepatocarcinoma cell . 38. The data indicated that the volumes of the popliteal and inguinal lymph nodes were significantly larger than the iliac artery lymph nodes . (2005) ISBN: 0471692735. Four months before admission, the patient started to present with mild diffuse abdominal pain, hyporexia, increased abdominal volume, dry cough, anterior chest pain, and loss of 4 kg in the last mouth. Hepatology. More advanced cases, such as the one presented in this study, are eligible to palliative treatment with sorafenib. HPB (Oxford). Case 2: metastatic cecal adenocarcinoma, polycystic liver and kidney, Case 4: dynamic MRI with hepatocyte-specific agent, Case 10: from mucinous adenocarcinoma of colon, Case 16: extensive from lung carcinoma on PET, transient hepatic attenuation differences (THADs), ultrasound appearance of hepatic metastases, transient hepatic attenuation differences (THAD), World Health Organization 2001 classification of hepatic hydatid cysts, recurrent pyogenic (Oriental) cholangitis, combined hepatocellular and cholangiocarcinoma, inflammatory myofibroblastic tumor (inflammatory pseudotumor), portal vein thrombosis (acute and chronic), cavernous transformation of the portal vein, congenital extrahepatic portosystemic shunt classification, congenital intrahepatic portosystemic shunt classification, transjugular intrahepatic portosystemic shunt (TIPS), transient hepatic intensity differences (THID), total anomalous pulmonary venous return (TAPVR), hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease), cystic pancreatic mass differential diagnosis, pancreatic perivascular epithelioid cell tumor (PEComa), pancreatic mature cystic teratoma (dermoid), revised Atlanta classification of acute pancreatitis, acute peripancreatic fluid collection (APFC), hypertriglyceridemia-induced pancreatitis, pancreatitis associated with cystic fibrosis, low phospholipid-associated cholelithiasis syndrome, diffuse gallbladder wall thickening (differential), focal gallbladder wall thickening (differential), ceftriaxone-associated gallbladder pseudolithiasis, biliary intraepithelial neoplasia (BilIN), intraductal papillary neoplasm of the bile duct (IPNB), intraductal tubulopapillary neoplasm (ITPN) of the bile duct, multiple biliary hamartomas (von Meyenburg complexes), localized pain and tenderness due to capsular stretching, gastrointestinal tract (via portal circulation), essentially all metastatic solid malignancies, positive mass effect with distortion of adjacent vessels, hypoechoic: most common ~65% and is a concerning feature, cystic, calcified, infiltrative and echogenic appearances are all possible: see. 1 A). 2012;81(9):2127-32. Liver Transpl Surg 1998;4:477-82. [9,10], The predictors of the presence of extrahepatic metastases are: size and number of HCC nodules, presence of tumor vascular invasion or tumor biomarkers.[2]. Metastasis, the greatest clinical challenge associated with cancer, is closely connected to multiple biological processes, including invasion and adhesion. (2003) ISBN: 1588902366, 2. Se encontró adentro – Página 282Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. Hepatology 2009; 50: 1464–1474. Yasuda E, Kumada T, Takai S, Ishisaki A, Noda T, Matsushima-Nishiwaki R, Yoshimi N, ... European Association for the Study of the Liver; European Organization for Research and Treatment of Cancer. Cancer Imaging. [13,14] In Table 1, we detail HCC cases of mediastinal metastases reported in the literature. Note large heterogeneous hypervascular anterior mediastinal mass (arrow) posteriorly compressing the right atrium and pulmonary artery, HCC is one of the most common primary tumors worldwide, and its prognosis has improved over the past few decades with the assessment of tumor vascular pattern by imaging methods and the emergence of therapeutic procedures. Zhonghua Yi Xue Za Zhi (Taipei) 1999;62:891-5. This is the case report of an 80-year-old retired widower coming from São Paulo, southeastern Brazil. This dissertation, "Actopaxin: a Novel Regulator of Cell Migration and Invasion in Human Hepatocellular Carcinoma" by Lui, Ng, 吳磊, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to ... Su incidencia está en una tasa bruta de 10,8 . Factor kappa B Enhances Hepatocarcinoma Metastasis by Repressing Fibronectin Expression XiaoyingZhang,ShanrongLiu,TingsongHu,ShupengLiu,YingHe,andShuhanSun It is increasingly clear that hepatocellular carcinoma (HCC) has a distinct microRNA (miRNA) expression profile that is involved in malignancy; however, little is known about Blocking either CD11b and/or CD18 elicited a significant decrease in M2 exos-mediated HCC cell metastasis. Tumor formation was initiated by the s.c. injection of 10 6 hepatocarcinoma (He/De) cells into rats. Se encontró adentro – Página 137(2010 OCT 5) Seoul National University College of Medicine: Absence of symptom and intact liver function are positive prognosticators for patients undergoing radiotherapy for lymph node metastasis from hepatocellular carcinoma A report, ... 1. The American Journal of Surgery, Vol. Anticancer Drugs. Metastasis of hepatocellular carcinoma to the heart: unusual patterns in three cases with antemortem diagnosis. 1999;230(3):309. After the inoculation of H22 cells to the liver, mice were treated by i.v . Se encontró adentro – Página 188MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling. ... Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing ... The present study showed that, despite therapeutic advances and the use of target therapy, survival is very limited when tumor is advanced, diagnosis is made at a later stage, and there are distant metastases. {"url":"/signup-modal-props.json?lang=us\u0026email="}, Gaillard, F., Jones, J. Hepatic metastases. 1. E-Twenty Six variant gene 6 (ETV6) is a strong transcriptional repressor, associated with the development and progression of tumors. Practical Differential Diagnosis for CT and MRI. Hepatoma Res 2016;2:293-6 . Hepatocarcinoma: metastasis to the nose and paranasal sinuses Otolaryngol Head Neck Surg. The aim of this study was to define clinical outcome and prognostic determinants in patients with BM from HCC. Ann Surg. MRI guided adaptive radiation therapy is a new and unique method of liver tumor treatment for both primary and metastatic disease 16. The most frequent site of the first detectable metastasis was the lung (58 [39%] patients). Axial contrast-enhanced computed tomography (CT) slice (A) and coronal reconstruction of CT scan (B). QHF is expected to be developed as an effective drug against HCC metastasis. Tumori 2004;90:345-7. Extrahepatic metastases of hepatocellular carcinoma. Ibirapuera, 981, Indianópolis, 04028-000 São Paulo, Brazil. Se encontró adentro – Página 13442003 in separating hepatocellular carcinoma from metastatic carcinoma with dendritic cells loaded with hepatocellular carcinoma cells Oct ; 94 ( 10 ) : 851-7 . in fine - needle aspiration cytology . Saad RS , et al . [4] However, research has shown that treatment of intrahepatic lesions should not be contraindicated in the presence of extrahepatic metastasis. Bull Stom hepatocellular carcinomas: a case report. Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism Tae-Wook Chung , National Research Laboratory for Glycobiology and Department of Biochemistry and Molecular Biology, Dongguk University College of Oriental Medicine, Kyungju . Extrahepatic metastasis, which rarely involves the mediastinum, is associated with poor prognosis. Hepatocellular Carcinoma (HCC) is one of the most common malignant tumors, and high recurrence and metastasis are the major obstacles to successful treatment of HCC. A hepatocarcinoma with osseous metastasis. Se encontró adentro – Página 4756as Activation of protein kinase Calpha couples cell volume to hepatocarcinoma . ... Hepatology 1998 Oct ; 28 ( 4 ) : 1073-80 ( Eng . Abstr . ) ( Ita ) Metastasis of hepatocellular carcinoma to the night coke The transcriptional function ... Gene therapy with pCH510 suppresses orthotopic hepatocarcinoma and metastasis of ectopic tumor to liver. Metastatic hepatocellular carcinoma mimicking a solitary mediastinal tumor. It is important to emphasize that the diagnosis of our patient was based on the presence of mediastinal mass and hepatic lesions. [5,6] We present a case of an elderly patient admitted to our institution after being diagnosed with HCC and mediastinal metastasis. To study metastasis, we have in vivo established mammalian tumor cell lines, among them the hepatocarcinoma (He/De), the nephroblastoma (Ne/De), the melanoma (Me/De), the myeloblastic nephroma (My1/De and My2/De) cell lines. Patient staging was reassessed, showing evidence of growth of the mediastinal mass, which measured 11.0 cm × 6.3 cm × 7.7 cm at that time and was compressing the right atrium and the pulmonary artery [Figure 2]. Hepatic metastases from colorectal adenocarcinoma can potentially be treated with hepatic metastasectomy, since they may be the only site of metastatic disease. Jin Y, Wang S, Chen W, Zhang J, Wang B, Guan H, Tang J (1). Authors J Izquierdo 1 , M Armengot, R Cors, A Pérez, J Basterra. cinoma and the metastasis of ectopic tumor to the liver. [3,4], Non-invasive diagnosis is made by imaging techniques, such as computed tomography and/or magnetic resonance imaging,[4] based on the vascular findings for these tumors, which exhibit a hypervascular pattern during the arterial phase and a washout pattern during the portal venous or delayed phase. Pancreatic neuroendocrine tumor liver metastasis in a patient with previously diagnosed pancreatic adenocarcinoma: an unexpected diagnosis Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic and clinical studies related to cancer cell, cell biology, oncology, radiation therapy and radiology, obstetrics and . Annexin A7 suppresses lymph node metastasis of hepatocarcinoma cells in a mouse model.

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